A Chinese speaker needs to use Chinese wh-word in this type of interrogatives, such as shen2me什么 “what”, shui2 谁 “who”, zen3me(yang)怎么(样) ”how”, wei4shen2me为什 or gan4ma2干吗 “why”, duo1shao3多少 “how much/many”, ji3-CL几-CL “how many”, nei3xie1那些 “which ones”, nei3-CL “which one”, and nar3哪儿 or na3li3那里 “where”, for examples:
你说什么? “What did you say?”
什么东西这么好吃? “What stuff is so tasty?”
你说谁? “who did you say?”
谁家有游泳池? “whose home has a swimming pool?”
他怎么样了? “How is he?”
他没有车,怎么去? “He does not have a car. How can (he) go?”
你干吗去? “Why did you go?”
你干什么去? “Why did you go?”
你为什么不听话? “Why did you not listen?”
你们有多少钱? “How much money do you have?”
你孩子今年有几岁? “How old is your child?”
哪些人想跳舞? “Which of these people want to dance?”
Reference
Sun, Chaofen (2006). Chinese: A linguistic introduction. Univ of California Press. Cambridge: Cambridge University Press.